ABSTRACT Frequent recombination is a hallmark of retrovirus replication.In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health.These recombinants may initially have substantial replication defects due to impaired interactions between protei
NK cell depletion in bispecific antibody therapy is associated with lack of HIV control after ART interruption
Abstract Deodorants HIV infection remains incurable as the virus persists within a latent reservoir of CD4+T cells.Novel approaches to enhance immune responses against HIV are essential for effective control and potential cure of the infection.In this study, we designed a novel tetravalent bispecific antibody (Bi-Ab32/16) to simultaneously target t
SCRAPPER Regulates the Thresholds of Long-Term Potentiation/Depression, the Bidirectional Synaptic Plasticity in Hippocampal CA3-CA1 Synapses
SCRAPPER, which is an F-box Collections protein encoded by FBXL20, regulates the frequency of the miniature excitatory synaptic current through the ubiquitination of Rab3-interacting molecule 1.Here, we recorded the induction of long-term potentiation/depression (LTP/LTD) in CA3-CA1 synapses in E3 ubiquitin ligase SCRAPPER-deficient hippocampal sli
Volcanic Ash Retrieval Using a New Geostationary Satellite
The paper presents currently developing method of volcanic ash detection and retrieval for the Geostationary Korea Multi-Purpose Satellite (GK-2A).With the launch of GK-2A, aerosol remote sensing including dust, smoke, will begin a new era of geostationary remote sensing.The Advanced Meteorological Imager (AMI) onboard GK-2A will offer capabilities